ceesdekker.net Secrets
ceesdekker.net Secrets
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2009, discovery of a completely new phenotype for germs in slim nanofluidic slits; and 1st detection of local protein structures along DNA using strong-state nanopores
Our team experiments bacterial mobile division and is also aiming to constitute a ‘base up biology’ in synthetic cells that may autonomously divide. Our main desire lies in cell division, chromatin structure, and spatial control.
Multicolor imaging on the bacterial nucleoid and cell division proteins with blue, orange, and close to-infrared fluorescent proteins
Due to the fact 2000, Dekker has shifted the primary emphasis of his work in the direction of biophysics wherever he studies the Homes of solitary biomolecules and cells utilizing the tools of nanotechnology. This variation of subject was pushed by his fascination for the amazing functioning of biological molecular buildings, as well as through the very long-time period perspective that lots of interesting discoveries could be predicted in this discipline.[five] Current lines of analysis in his biophysics team are within the regions of:[6]
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and very first at any time research from the dynamics DNA supercoils and the invention of supercoil hopping
Experimental phase diagram of negatively supercoiled DNA calculated by magnetic tweezers and fluorescence,
You're a Christian. If you may make such a artificial cell, would you be a person action closer to God, or would the purpose of God have diminished fairly again?
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‘You shouldn't just think of the issues of tomorrow, and also evaluate the thoughts of your working day immediately after tomorrow’
Dekker started off his investigation on single carbon nanotubes in 1993 when he arrange a whole new line of study to check electrical transportation by means of one organic and natural molecules in between nanoelectrodes. In 1996 a breakthrough was understood with carbon nanotubes. This was reached inside a collaboration While using the group of Nobel laureate Richard Smalley. STM and nanolithography techniques ended up accustomed to demonstrate that these nanotubes are quantum wires at The only-molecule level, with fantastic physical Homes.
Considering the fact that 2000 he moved to solitary-molecule biophysics and nanobiology, with analysis from experiments of DNA loop extrusion and supercoiling to DNA translocation by way of nanopores. Much more a short while ago his investigation has focused on finding out chromatin construction and cell division with bacteria on chip, when he is additionally seeking to eventually build synthetic cells ceesdekker.net from The underside up.
Nanoscientist Cees Dekker is really an amiable and flamboyant male who appears A lot younger than the sixty two yrs he in fact is – trendy glasses, psychedelic shirt, partaking smile – but not a single to waste time. He usually takes his time, but not more than required.
2008, initially observation of protein-coated DNA translocation by nanopores; solved the origin with the electrophoretic pressure on DNA in nanopores; uncovered a big velocity enhance of microtubules in electric powered fields; learned an anomalous electro-hydrodynamic orientation of microtubules; and solved the origin of sound in carbon nanotubes in liquid
Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij met enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart design in 2005. (nl)